SCAN-B MutationExplorer

Gene Stat Angle Cell Pvalue Qvalue A1BG 1.07177295114858

Genes; ITPKA; ITPKA (Inositol-trisphosphate 3-kinase A) active profile. Protein names. Recommended name: Inositol-trisphosphate 3-kinase A. Short name: IP3K A. Alternative name(s): Inositol 1,4,5-trisphosphate 3-kinase A IP3 3-kinase A InsP 3-kinase A. Top Gene-Substance Gene. Itpka. Species Mouse Transcripts. 1 RefSeq (NM) Transcript Type Coding Product Type Silencer® Select Availability. Made to Order.

Itpka gene

This view is a gene level view. To access the transcript level displays select a Transcript ID in the table above and then navigate to the information you want using the menu at the left hand side of the page. dramatically down-regulated ITPKA expression in all OSCC cell lines examined. ITPKA protein encoded by the gene located on chromosome. 15q14-q21 is Genes. HSA: 3706(ITPKA) 100988859(ITPKA).

Induced > 3x by LPS @ 1h 445 A B C D E F G H I J K L M N O P Q

Inositol 1,4,5-trisphosphate 3-kinase (ITPK) catalyzes the phosphorylation of Ins (1,4,5)P3 to Ins (1,3,4,5)P4, both of which are modulators of calcium homeostasis. Plasmid ITPKA_3xmScarletI from Dr. Dorus Gadella's lab contains the insert ITPKA and is published in bioRxiv 160374 This plasmid is available through Addgene. Figure 1 ITPKA is screened out as a promoter in RCC and positively correlated with RCC malignancy and poorer prognosis.

Gene Stat Angle Cell Pvalue Qvalue A1BG 1.07177295114858

Plasmid ITPKA_3xmScarletI from Dr. Dorus Gadella's lab contains the insert ITPKA and is published in bioRxiv 160374 This plasmid is available through Addgene.

Official gene symbol, which is typically a short form of the gene name, according to HGNC. ITPKA. Gene descriptioni. ITPKA Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, ITPKA Genome Browser, ITPKA References ITPKA - Explore an overview of ITPKA, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data. Itpka - Inositol-trisphosphate 3-kinase A - Rattus norvegicus (Rat) - Itpka gene & protein UniProtKB - P17105 (IP3KA_RAT) GuideToPharmacology Gene Category Name: Inositol 1,4,5-trisphosphate 3-kinases: GuideToPharmacology Gene Category ID: 280: Gene Biotype: PROTEIN_CODING Gene information about ENSG00000137825 / ITPKA - inositol-trisphosphate 3-kinase A Itpka MGI Mouse Gene Detail - MGI:1333822 - inositol 1,4,5-trisphosphate 3-kinase A. View mouse Itpka Chr2:119742337-119751253 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression. Home. Gene symbol: ITPKA: Gene name: inositol-trisphosphate 3-kinase A: Chromosome: 15: Chromosomal band: q15.1: Imprinted: Unknown: Genomic reference: NC_000015.9: Transcript reference: NM_002220.2: Associated with diseases-Citation reference(s)-Curators (1) Global Variome, with Curator vacancy: Total number of public variants reported: 3: Unique Despite recent advances in cancer therapy, the overall 5-year survival rate of patients with lung cancer remains low.
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ITPKA Gene Body Methylation Regulates Gene Expression and Serves as an Early Diagnostic Marker in Lung and Other Cancers. Wang YW, Ma X, Zhang YA, Wang MJ, Yatabe Y, Lam S, Girard L, Chen JY, Gazdar AF The C-terminal part of ITPKB, namely residues 187 to 462, was 68% identical to ITPKA in amino acid sequence.

GGO: 101142571(ITPKB) 115930848(ITPKA). PON CSAB: 103229987(ITPKB) 103245796(ITPKA).
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Induced > 3x by LPS @ 1h 445 A B C D E F G H I J K L M N O P Q

Orthologous to human ITPKA (inositol-trisphosphate 3-kinase A). ITPKA is expressed in a broad range of tumor types but shows limited expression in normal cells. In lung and breast cancer expression of ITPKA is stimulated by gene body methylation which increases with increasing malignancy of these tumors but is not detectable in the corresponding normal tissues. Gene: Itpka - ENSRNOG00000005284 - Rattus norvegicus (rat) General information. Ensembl ID: ENSRNOG00000005284: Name: Itpka: Description RefSeq summary [ITPKA] Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4.